The results given by NIPT using maternal blood, though checks for chromosomal anomalies in the cell-free fetal DNA, it is still considered as screening; indicating in case of a positive report, a physician may chose for the confirmatory invasive tests like amniocentesis or chorionic villi sampling (CVS) as per suspicion. These involve checking the amniotic fluid or cells from the chorionic villi directly for confirmation. These invasive procedures however bear a small risk of miscarriage. Similar is the case for serum-based antenatal screening tests. In case of positive risk prediction by a serum-double, triple or a quadruple marker test, the above confirmatory tests may be recommended.
The brand MyMaternity is your one-stop for all antenatal/prenatal screening needs. The tests under MyMaternity are the ones which are routinely prescribed by pregnancy care givers and includes both which are a necessity for routine screening and those which are specifically intended for the high-risk categories. The test menu has been designed to ensure a single diagnostic prescription can suffice a whole lot of mixed needs. We are associated with Thyrocare, an established preventive diagnostics and wellness service provider, MyMaternity aims to be your affordable prenatal care partner.
Once you have chosen the test you should go for as per the prescription given by medical experts, just simply click on the ‘Tests’ tab that appears under the top menu. Once you select test, the booking page will appear where you need to fill all the necessary details that are required to book the test package. Our team will handle the rest.
The complete details about the TAT for every test is given inside the test information page. Generally, 24-48 hours of time is required to generate the test reports. 24 hours are required for the EDTA-blood tests and serum tests and 48 hours are needed for the marker tests. However, all the necessary documents must be provided on time. Maximum 12 days can be required to generate Karyotyping test results as laboratory processing is needed for this.
The development of Chromosomal aneuploidies generally includes a certain number of risk factors. The chances of chromosomal aneuploidies remain the highest during the first week after getting pregnant, approximately 60%. Knowingly, it passively increases the risk of miscarriage. The chances are 1-2% for a 12 weeks old embryo.
Not exactly. MyMaternity has a wide variety of tests to choose from and you will be needing an expert’s opinion to know which test will suit you the most. For example, your need for a test will be depending on factors like your previous medical history as well as your acceptability.
Ultrasound (USG)
Karyotyping (Chromosomal structure with number analysis)
Maternal and Serum testing
Amniocentesis
Non Invasive Prenatal Test
Carrier screening tests
Chorionic Villi Sampling (CVS)
Single-Gene or Panel Gene Testing
Before performing any tests involving DNA or RNA or any other type of genetic test, this is mandatory to have a written informed consent. A standard written consent generally contains a brief detail about the purpose of the test and outcomes including the fate of newly generated genetic data. This is necessary for each participant as it helps to make a wise choice of tests.
All pregnant women are suggested to go for serum and blood based diagnostic tests. Tests that involve consent are usually recommended after completing a checkup for potential risk factors like history of smoking and drinking, maternal age, BMI of the carrying women or any family history of genetic abnormalities. Sometimes, this test is also recommended to assess the overall health.
Not really, it can not be used. Blood samples that are collected for NIPT are kept in EDTA anticoagulant tubes. On the other hand, blood samples that are collected for Karyotyping are kept in Sodium-Heparin tubes.
Screening tests can not be considered as confirmatory tests. If the screening report is positive, it means it is indicating the possibilities of risks. However, it can not be confirmed through screening that a patient is already at risk or not. Generally, physicians also recommend to go for confirmatory tests even after screening tests.
NIPT is recommended in case of high risk pregnancies and also to have confirmation about the need of invasive tests as this is merely an advanced screening tool. In a word, NIPT is mandatory to determine the exact needs of any invasive tests that might be needed. Besides, it also helps a couple to stay prepared for any future plannings of pregnancy even if having a positive result.
Low risk: This indication clearly means that the risk that has been detected for tested conditions of trisomy 21, 18 and 13 is actually low in the unborn baby.
High Risk: This indication means that the risk that has been detected for tested conditions of trisomy 21, 18 and 13 are high in the unborn baby.
Need for resampling: This specific kind of outcome is presented for a very little number of reports every time the received sample remains unmatched with our reporting criterias which are very strict. It may happen because of,
Insufficient amount of cffDNA in the patient’s blood
Arising sample integrity issues because of inadequate mixing of samples in the tube or improper venipuncture.
